Homestar Runner Bubsamecium is the proprietor of Bub5amecium's Protozoa Stand with Bubs's eyes and toothy mouth floating within the shifting blue mass. Bubsamecium appears to be shaped like the typical perception of an amoeba. This version of Bubs has appeared in Homestar Runner cartoon in high school episode where Patrick asks Strong Bad about his younger years. Strangely, Bubs is based on a person The Brothers Chaps knew growing up who worked at a concession stand locally and spoke with the same gravelly voice. A fanart Homestar Runner cursor with Bubsamecium.